| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69acaefdafb0c568e4a8788890c3de74 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1277
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-008 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| filingDate |
1991-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6774b8678d61992c6acb1d858715437d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26fa01a62bce4ff80016de061bd6a556
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8db58d7664602c0991b44f6f320de504
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9c71b652154453abc0f4edef3edb119
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b425c3c7bd1e32d49c3201f5ea3abf83 |
| publicationDate |
1991-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2081474-A1 |
| titleOfInvention |
Direct spray-dried drug/lipid powder composition |
| abstract |
The present invention discloses a method for direct spray-drying a solution of lipids and water soluble drug to generate a bulk powder as an alternative to the drying of preformed liposomes. In the present method the lipids are dissolved in a solvent and the water-soluble drug is dissolved in aqueous solvent. The two solutions are combined to form a precipitate-free feed solution which is then spray-dried to generate the bulk powder. Upon rehydration the powder spontaneously forms liposomes having a high drug encapsulation efficiency of approximately 70 %. The direct spray-dried powder is particularly useful for drug administration by inhalation. |
| priorityDate |
1990-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |