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filingDate 1992-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1996-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a93ce243bc4c79fff97d28af65e3583
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e016486248503993114558a3834ec5ec
publicationDate 1996-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2077418-C
titleOfInvention Process for production of prostaglandin intermediates
abstract The present invention is directed to improving the isomer ratio of a cis-isomer as compared to the corresponding trans-isomer with respect to the 5-6 double bond in the production of prostaglandins. The improvement is achieved when a lactol is reacted with an ylide to cause simultaneous formation of the 5-double bond and an .alpha.-chain, whereby the ylide generated from a phosphonium salt with a potassium base, and a solvent which is liquid at the reaction temperature and has a dipole moment of 0.3 to 3.0D are used.
priorityDate 1991-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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