Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76dd936792fdbd79e17f602e6aa86789 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f2e5f32fabebf66e55e9edde46f633a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_528b492b39636c59df6aab92c6319496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a5cd3ef7ca508377b835e28a7b9b433 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-475 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
filingDate |
1991-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d264d18bc04af8e3f97e0d4c680ba3a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_875301132c1f406fe99ccf7c6ca124d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58145b03a0f909defe469bb3a6b25645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57b3055e80b84677c51b2af577556f90 |
publicationDate |
1992-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2077350-A1 |
titleOfInvention |
Dna coding for growth-inhibitory factor and use thereof |
abstract |
A DNA which codes for a novel protein GIF which inhibits neurotrophic activity and which is present in the brain of a healthy man but is not in the brain of a patient with Alzheimer's disease has been cloned from a human cerebral cDNA library and a human genome DNA library. Escherichia coli has been transformed by a vector containing the cDNA integrated thereinto to express the GIF. The DNA which codes for a cloned GIF can be used in the genetic diagnosis and treatment of Alzheimer's disease and a large amount of the GIF can be produced by expressing said DNA in a transformant. |
priorityDate |
1990-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |