| abstract |
Abstract Compounds of the formula I wherein R signifies a residue of the formula , or , (a) (b) (c) and R1, R2, R3, R4, R5, R6, R7, X, Y and Z have the significance given in claim 1, with the exception of rac-N-(3,4-dimethoxy-phenethyl)-2-(3,4-dimethoxyphenyl)-.beta.,N-dimethyi-m-dithiane-2-propylamine, as well as their acid addition salts have outstanding properties against multi-resistant malignant tumour cells and against chloroquine resistance, and are accordingly suitable for reducing and/or eliminating multiple resistance to cytostatics in the treatment of tumours or for reducing and/or eliminating chloroquine resistance in the treatment of malaria. |