| abstract |
Disclosed is a compound containing a 2-amino-7-(R)-3H,5H-pyrrolo[3,2-a]pyrimidin-4-one wherein K is cyclohexeny cyclohexyl, or -CH2-R1, and wherein R1 is an optionally substituted heteroalicyclic, pyridinyl or alicyclic group. Also dis-closed is a compound of formula (I), wherein R1 is H, NH2, or OCH3, R2 is an optionally substituted cyclic group of 5-carbon atoms optionally containing one or more heteroatoms, R3 and R4 are independently H or C1-4 alkyl, m is 0-4, n is 0-6, p is 0-1, X is CN, CSNH2, PO(OH)2, COOH, SO2NH2, NH2, OH CNHNH2, tetrazole, or triazole, COR5 where R5, C1-4 alkyl, CF3, NH2, or OC1-4 alkyl, and Y is O or NH. |