http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2072080-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d14740313c629a05795f84de38972407 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-08 |
| filingDate | 1991-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eff3322fc4df2f0f4bbb3ed7092fd7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30c9630ec5fd915f6666706c989ad374 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd5b3ab9f7fc14547ca6d432aa82d040 |
| publicationDate | 1991-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2072080-A1 |
| titleOfInvention | Chelating compounds |
| abstract | The invention provides novel condensed macrocylic chelants of formula [X(CR2R3)n]m, (wherein each X independently represents an oxygen or sulphur atom or a group of formula NH, N(CR2R3)pR4, N(CR2R3)pY, or N(CR2R3)n-N((CR2R3)pY)2; each Y independently represents a group COZ, SO2Z, POZ2, CON(OH)R2, CH2SR2, CS2R2 or CSZ; each Z independently represents a group OR2 or NR2R2; n is an integer of 1 to 4; m is an integer of 3 to 8; p is an integer of 1 to 3; each R2 independently represents a hydrogen atom or a C1-8 alkyl group optionally mono- or poly- substituted by hydroxyl or C1-8 alkoxy groups and at least one pair of R2 groups, in each pair one being from a (CR2R3)n moiety and the other being from a (CR2R3)n or (CR2R3)p moiety, together with the intervening atoms represents a 5 to 8 membered, saturated fused ring optionally containing one or more ring heteroatoms selected from nitrogen, oxygen and sulphur, said fused ring optionally being substituted by a group R1; each R1 independently represents a group R4 or a nitrogen-attached group (CR2R3)pY; each R3 independently represents a hydrogen atom or a C1-8 alkyl or C1-8 alkoxy group optionally mono or poly substituted by hydroxy or C1-8 alkoxy groups; and each R4 independently represents a hydrogen atom, a halogen atom or a hydroxyl group or an optionally mono- or poly-hydroxylated C1-8 alkyl, C1-8 alkoxy, (C1-8 alkoxy)- C1-8 alkyl or poly- (C1-8 alkoxy)- C1-8 alkyl group, a sulphonate group or a group (CR2R3)pY; with the proviso that at least 2 Y groups are present). These chelants are useful in the preparation of diagnostic and therapeutic agents, in particular chelate complexes suitable for use as contrast agents for diagnostic imaging techniques, e.g. MRI. |
| priorityDate | 1990-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 98.