| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0202 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-22 |
| filingDate |
1992-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2003-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d64503d7f7ff9a893d45b890b7b7c3f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcb9287403ce23f0bba53309311c7a76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9227d78a06cd877ab0264bdb49465143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11c7d357fa4ca399863eb4fdbe0d2f00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbd3926c888a38bfb77f73a6e7b5a862
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cb99a60c39931855ee885f715734559 |
| publicationDate |
2003-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2071674-C |
| titleOfInvention |
Peptidyl derivatives as inhibitors of interleukin-1.beta. converting enzyme |
| abstract |
Novel peptidyl derivatives of formula I are found to be potent inhibitors of interleukin-1.beta. converting enzyme (ICE). Compounds of formula I may be useful in the treatment of inflammatory or immune-based diseases of the lung and airways; central nervous system and surrounding membranes; the eyes and ears; joints, bones, and connective tissues; cardio-vascular system including the pericardium; the gastro-intestinal and urogenital systems; the skin and mucosal membranes. Compounds of formula I are also useful in treating the complications of infection (e. g., gram negative shock) and tumors in which IL 1 functions as an autocrine growth factor or as a mediator of cachexia. (See formula I) |
| priorityDate |
1991-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |