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filingDate 1992-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d78b65f00ee879d6324dd9db3585e2fb
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publicationDate 1992-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2064349-A1
titleOfInvention Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenylpropionic acids
abstract Mixtures of enantiomeric D,L-threo 2-amino-3-hydroxy-3-phenylpropionic acids can be stereoisomerically enriched by contacting the mixture with a D-threonine aldolase. In a typical embodiment, D- and L-threo 2-amino-3-hydroxy-3-(4-methylsulfonylphenyl)propionic acid is treated with D-threo-nine aldolase to produce L-threo 2-amino-3-hydroxy-3-(4-methylsulfonylphenyl)propionic acid with a high ee. The benzaldehyde and amino acid formed from the D-threo isomer can be recycled.
priorityDate 1991-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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