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filingDate 1990-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43fa3f741832c2a28b3c4805106f3815
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a44fed22f78260d22c0620831c0a1de
publicationDate 1991-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2064035-A1
titleOfInvention Shelf stable aspirin solutions
abstract There is provided a shelf stable solution of aspirin, free of moieties reactive with aspirin, suitable for topical application to the skin compounded from aspirin, N,N-diethyl-m-toluamide USP (DEET), glyceryl triacetate USP (GTA), and acetic anhydride, provided that where GTA is present, at least 20 parts of DEET shall also be present and, after all components shall have been mixed, the resultant solution shall contain an initial amount of between about 1 and about 0.2 parts of acetic anhydride. The solution is made by preparing a solvent component consisting of at least N,N-diethyl-m-toluamide USP (DEET), and, if desired, glyceryl triacetate USP (GTA), provided that where GTA is present, at least 20 parts of DEET shall also be present, assaying said solvent mixture to determine the hydroxyl content, adding sufficient acetic anhydride to provide between about 1 to about 0.2 parts of unreactive acetic anhydride in the solution after dissolution of the aspirin therein, and dissolving aspirin, thereinto.
priorityDate 1989-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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