abstract |
ABSTRACT This invention provides a process for producing drug-containing nanoparticles by combining a drug, a volatile, water-miscible, surface tension-reducing organic solvent, a polymer selected from poly(lactic) acid, poly(glycolic) acid or co-poly(lactic/glycolic) acid, and optionally a volatile drug-dissolving organic solvent, mixing with an aqueous solution of polyvinyl alcohol, emulsifying, removing the organic solvents, and separating the nanoparticles. |