http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2060267-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6841 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 1992-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b88683040bb00f03a2f374724075733 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f28274a9e3d333c64e93cba2f07a3345 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7a2603a8ba11c4a6d1169095f21a891 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d2b6e4c182e6ae822eebd5710f3e604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a76b3a1d592119d100de51104aa4162 |
publicationDate | 1992-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2060267-A1 |
titleOfInvention | Chromosome specific staining to detect genetic rearrangements |
abstract | CHROMOSOME-SPECIFIC STAINING TO DETECT GENETIC RE~RRANGE~ENTS ~STRACT OF_THE DISCLOSURE Provided ar~ methods and compositions ~or stainlng chromosomal material based upon nucleic acid se~uence employing high complexity nucleic acid probes ~herein t:he staining pattern produced is indicative of the presence or absence of one or more genetic rearrangements involvlng chromosomes 3, 13 and/or 17. Said probes are appropriate for in situ hybridi~ation and stain both int~rphase and metapha~e chromosomal material with reliable signals. The staining methods can be used in conjunction with digital image analysi~. Probes and test kits are provided ~or use in detecting genetic rearrangements, particularly those related to tumor suppre~sor genes~ in the detection of disPase related loci, specifically cancer, such as retinoblastomas, ost~osarcomas, lung cancer, breast cancer, oYarian and uterine cancers, and for biologica} dosimetry. Re~erence probes, for ~xample, centromeric alph~ satellite probes, can be a component of the high complexity probes. |
priorityDate | 1991-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 172.