http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2057868-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da5ac784fcbb213313bda68dda9907b4 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D257-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6524 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6524 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F- |
filingDate | 1991-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e2c1489ce6e91f7152d13d2fbf16042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d85946456effc8e33699b74691d70af |
publicationDate | 1991-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2057868-A1 |
titleOfInvention | Tetra-aza macrocycles processes for their preparation and their use in magnetic resonance imaging |
abstract | Metal complex of tetra-aza macrocycles of formula (1) wherein Alk1, Alk2, Alk3 and Alk4, which may be the same or different, is each a C1-4 alkylene chain optionally substituted by one or more optionally substituted C1-6 alkyl groups; and R1, R2, R3 and R4 which may be the same or different is each a hydrogen atom or a group AlkR5 where Alk is an optionally substituted straight or branched C1-6 alkyl group and R5 is a hydrogen atom or a -CO2H,-CONR6R7 [where R6 and R7, which may be the same or different, is each a hydrogen atom or a C1-6 alkyl group] or -P(X1)(X2R8)R9 group where X1 and X2, which may be the same or different is each an oxygen or sulphur atom, R8 is a hydrogen atom or an alkyl group and R9 is an aliphatic, aromatic or heteroaromatic group, with the proviso that at least two of R1, R2, R3 and R4 is a group -AlkP(X1)(X2R8)R9 or one of R1, R2, R3 and R4 is a group -AlkP(X1)(X2R8)R9 and at least one of the remaining groups R1, R2, R3 and R4 is a group -AlkCO2H or -AlkCONR6R7, or a salt thereof, for use as contrast agents in nuclear magnetic resonance imaging are described. |
priorityDate | 1990-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 87.