abstract |
ABSTRACT New leukotriene B4 analogs of Formula I (I), wherein R1 stands for the COOR2 radical with R2 standing for a hydrogen atom or a (C1-C4) alkyl group or R1 stands for the CH2OH radical, B stands for an alkylene group with 1-3 carbon atoms in the chain, a radical or a radical with R3 standing for a hydrogen atom, a carboxy or a methoxycarbonyl group, A stands for the groups , -O-, -?-, -NH-CO-, -CO-NH-, -OCH2-, -CH=CH-, -C?C-, -COCH2-, or -CHOH-CH2-, X stands for N or CH, D stands for the groups or and is a simple or double bond, and, optionally, the salts of these with physiologically innocuous bases, and a process for the production of these, and their pharmaceutical use. |