abstract |
Compositions suitable for intraveneous injection are disclosed, which comprise a stabilizing buffer solution containing IgM antibodies. The compositions are effective in stabilizing the antibodies in solution, inhibiting precipitation and the formation of particulates in the final product vial, while maintaining a high level of immunoreactivity. The compositions can be lyophilized to form dry, stable products which can be readily reconstituted to provide injectable, particle-free antibody solutions. |