http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2046016-C
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 |
| filingDate | 1991-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2002-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25ee5cdd61c3e8467c92b8f7a5eb3cd8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11a3a2a08b79725d5b46ac9ccc91a1b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f1f858fb6d4293f717b856c46dd62cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecfca4b6d816ee2cdd225c2ed87e3bbf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e95f676f98af285ce1044153bdf0a21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2715c7a28ff45967a2cef56daaaf9df1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6437e0b51bd15875d076ddad4ab0f9f |
| publicationDate | 2002-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2046016-C |
| titleOfInvention | Hiv monoclonal antibody |
| abstract | A monoclonal antibody is described capable of binding to a glycoprotein antigen having a molecular weight of about 12 x 10 4 daltons (gp120) present in the envelope of human immunodeficiency virus (HIV) and capable of substantially neutralizing the HIV, or fragments thereof. It has the characteristics of immunoglobulin class IgG, k, being capable of binding to glycoprotein antigen having a molecular weight of 12 x 10 4 daltons (gp120) of HTLV-III MN, being capable of recognizing at least one epitope which is present in the region of the amino acid sequence 303 to 325 of gp120 of HTLV-III MN, being capable of binding to the surface of HTLV-III MN viral particles and thereby inhibiting the infection of the viral particles to CD4-positive cells, and being capable of binding to the surface of cells infected with HTLV-III MN and thereby inhibiting the syncytium formation induced by interaction between the infected cells and uninfected cells. The monoclonal antibody is useful for the prophylaxis, treatment and diagnosis of AIDS. |
| priorityDate | 1990-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 121.