Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60442fdc20fd71481fc3d6b8cdee2c31 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D463-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D477-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D463-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 |
filingDate |
1991-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe03a7787b46c59fb92bd49504a1c335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd88b241ca4119e7ba86c36ccfd568d8 |
publicationDate |
1991-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2043939-A1 |
titleOfInvention |
Process for bicyclic .beta.-lactams |
abstract |
ABSTRACT 1-Carbapenam-2-one-3-carboxylic acid and 1-carba-3-hydroxy-3-cephem-4-carboxylic acid and esters thereof are provided by a process comprising a rhodium C2-C10 carboxylate catalyzed cyclization of an ester of a 4-(1-alkoxy- or 1-substituted alkoxy)-2-oxo-4-azetidinyl)-.alpha.-diazo-.beta.-ketobutyric acid and an ester of a 5-(1-alkoxy- or 1-substituted alkoxy-2-oxo-4-azetidinyl)-.alpha.-diazo-.beta.-ketovaleric acid respectively. The process is carried out in an inert organic solvent at a temperature between about 15° C and about 85° C. The 1-carba bicyclic .beta.-lactams are intermediates for preparing antibiotics. |
priorityDate |
1990-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |