| abstract |
ABSTRACT OF THE DISCLOSURE This invention relates to cyclobutane derivatives represented by the following general formula (1) and physiologically acceptable salts thereof: (1) wherein B represents a nucleic acid base derivative, R1 and R2 independently represent hydrogen atom, dialkyl-aminoacyl group, 1,4-dihydro-1-methylnicotinoyl group or substituted phosphoric acid group, provided that either one of R1 and R2 is a group other than hydrogen atom. The compounds of this invention exhibit a high oral absorbability and are metabolized in vivo into the compounds of formula (1a). Accordingly, the compounds of this invention are expectedly useful as antiviral agent. |