| abstract |
Abstract A method of inhibiting bone demineralization comprising administration of an effective amount of a compound having the formula where X is CH or N; Y is O or S; R1 is 2-propenyl, C1-C3 alkyl. benzyl or substituted benzyl where the substitutents are one or two of the same or different and are selected from methyl, ethyl, methoxy, ethoxy, hydroxy, chloro, bromo, or fluoro; R2 is C2-C3 alkyl, allyl or cyclopropylmethyl; R3 and R4 are both hydrogen or combine to form a carbon-carbon bond; and pharmaceutically acceptable acid addition salts thereof to a mammal requiring bone demineralization inhibition. |