http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2042870-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d73846b93d70b4ac73e5adaf7e5e01b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-785 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-80 |
| filingDate | 1991-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db97cdb1794db2ab1ac035b16cff2f53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c465595b43e3a27810d11612400b1c45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1aa215416694319f327410ecce5f6001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0fa376e50a6bfb1a41a9e70b56de110 |
| publicationDate | 1992-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2042870-A1 |
| titleOfInvention | Metal ion coordinated polyamine resins for the lowering of blood cholesterol |
| abstract | The invention is concerned with a metal ion coordinated polyamine resin in which a non-toxic, pharmaceu-tically acceptable chelating metal ion is coordinated with a cross-linked and non-digestible polymeric amine selected from the group consisting of: (a) polyamine resins with a hydrophilic backbone, of the formula: P-[(CH2)nNH]mH or (Ia) (Ib) wherein P represents a hydrophilic, cross-linked and non-digestible homopolymer backbone, m is an integer varying from 1 to 10 inclusive, and n, o and p are, independently, integers varying from 2 to 12 inclusive; (b) polyamine resins with a hydrophobic backbone, of the formula: P'-[NH(CH2)n]mNH2 (II) wherein P' represents a hydrophobic, cross-linked and non-digestible homopolymer backbone, m is an integer varying from 0 to 6 inclusive and n is an integer varying from 2 to 12 inclusive; and (c) cross-linked copolymers of a poly-ethylenepolyamine containing from 2 to 6 ethylene units and epichlorohydrin. The metal ion coordinated polyamine resins of the invention are highly efficient sorbents for bile acids and salts and can thus be used for reducing hyper-cholesterolemia in affected humans. |
| priorityDate | 1991-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.