Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4cdf984e52e386742b6ba53f2672f7d3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16122 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 |
filingDate |
1991-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c042565263a6cc5159498c7291144c8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67ab0946ddad4fc4acc3c8f1d09e45cf |
publicationDate |
1991-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2042085-A1 |
titleOfInvention |
Process for the preparation of retrovirus immunogens and vaccines against retroviral, notably hiv, infections and obtained immunogens and vaccines |
abstract |
ABSTRACT A PROCESS FOR THE PREPARATION OF RETROVIRUS IMMUNOGENS AND VACCINES AGAINST RETROVIRAL, NOTABLY HIV, INFECTIONS AND OBTAINED IMMUNOGENS AND VACCINES The supernatant from a retroviral particle culture such as HIV is inactivated in two steps with beta-propiolactone at low temperature and high temperature, then concentrated by ultrafiltration, subjected to gamma-irradiation, purified, preferably, by dialysis, then gel filtration and ion exchange chromatography, and heated to 60°C during at least one hour. Application for immunogens and HIV vaccines. |
priorityDate |
1990-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |