| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75b30ff8273a54b655e5eb2eed62b4b1 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate |
1990-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2006-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_776acb0a212877b6f1c21e153cf750b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d4351209b0c41c0fb0a9511f1162a40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1050f3bc54083a205dd29de4fe3fa0e2 |
| publicationDate |
2006-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2037907-C |
| titleOfInvention |
Homologous recombination for universal donor cells and chimeric mammalian hosts |
| abstract |
Homologous recombination is employed to inactivate genes, particularly genes associated with MHC antigens. particularly, the .beta.2-microglobulin gene is inactivated for reducing or eliminating Class I MHC antigens. The resulting cells may be used as universal donors. In addition, embryonic stem cells may be modified by homologous recombination for use in producing chimeric or transgenic mammalian hosts. |
| priorityDate |
1989-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |