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filingDate 1990-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1992-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2031455-A1
titleOfInvention Method for producing hybridoma antibodies and their use
abstract ABSTRACT OF THE DISCLOSURE A method is disclosed for producing hybridoma cell lines by fusion of immunized splenocytes of the mouse with mouse myeloma cells. The splenocytes are immunized against interleukin-6 prior to the fusion. Three different cell ines can be identified and isolated from the fused cells, that is the hybridoma cell line with the C.N.C.M. deposition number I/913 (BE-8), the hybridoma cell line with the C.N.C.M. depositon number I/911 (BE-4) and the hybridoma cell line with the C.N.C.M. deposition number I/912 (BF-6), which produce monoclonal antibodies which recognize human interleukin-6 and which in dependence upon the different cell lines each bind themselves to a different epitope on the interleukin-6 molecule.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8017121-B2
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type http://data.epo.org/linked-data/def/patent/Publication

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