| abstract |
Disclosed are neutral sugar derivatives of pradimicins (BU-3608 antibiotics), their use as antifungal agents, methods for their preparation and intermediates for their synthesis. Said derivatives include a compound having the formula (see fig.I) wherein R1 is selected from the group consisting of H and hydroxymethyl, and when R1 is hydroxymethyl, the resulting amino acid residue has the D-configuration; and R2 is H or .beta.-D-xylosyl or a pharmaceutically acceptable salt thereof. |