http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2029289-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c24684033fba97d1ad845ce453a57e3 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 |
filingDate | 1990-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f914afd2b0dba3793a85171f17b2601 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b23d841ef51cdc09fcc6309c2b091284 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0600c658d8e6369dfbe96237927f5487 |
publicationDate | 1991-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2029289-A1 |
titleOfInvention | Insulin derivatives, process for their preparation, their use and a pharmaceutical preparation containing them |
abstract | Abstract of the disclosure: Novel insulin derivatives, process for their preparation, their use and a pharmaceutical preparation containing them Novel insulin derivatives of the formula III (III) in which a) R30 + R31 together = OH or b) R30 = a radical of a neutral, genetically encodable L-amino acid and R31 = OH or a physiologically acceptable organic group of basic character having up to 50 carbon atoms, whose synthesis involves 0 to 3 .alpha.-amino acids and whose optional terminal carboxyl function can be present free, as an ester function, as an amide function, as a lactone or reduced to CH2OH, and c) RA-1 = a radical of a genetically encodable L-amino acid or a physiologically acceptable organic group having up to 50 carbon atoms, with the exception of the case in which, at the same time, R30 = Ala, R31 = OH, RA-1 = Lys or Arg and the A and B chain are the sequences of bovine insulin, and its physiologically tolerable salts. The compounds are suitable for the treatment of diabetes mellitus, have a sustained action profile and are very well tolerated. |
priorityDate | 1989-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 154.