http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2028530-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C275-40 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 1990-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_033f175937882d6b6bacfb34695a95bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56b28685822e5242bfabf27c7a7081ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f02eadb7dd685b522cf7ff0db7298fa9 |
| publicationDate | 1991-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2028530-A1 |
| titleOfInvention | Substituted pyrimidobenzimidazole derivatives |
| abstract | Abstract The present invention is concerned with novel substituted pyrimidobenzimidazole derivatives of the general formula wherein R1 signifies hydrogen, halogen or amino, R2 signifies halogen, R signifies a lower alkyl-substituted 4-pyridyl group or a group R3R4N- in which R3 and R4 each signify hydrogen or lower alkyl or together signify a group of the formula -(CH2)n-X-(CH2)m- or -(CH2)p-which is unsubstituted or substituted by lower alkyl, amino, lower aminoalkyl, mono- or di(lower alkyl)-amino-lower alkyl, oxo or the group -COOR2 or -CONR'R", n and m each signify the number 1, 2 or 3, with the proviso that n + m is a maximum of 5. p signifies the number 4, 5 or 6, X signifies an oxygen or sulphur atom or the group -NR"'-, Ra signifies hydrogen, lower alkyl, lower alkenyl, phenyl or phenyl which is mono-, di- or trisubstituted by halogen, lower alkyl or hydroxy, R' and R" each signify hydrogen or lower alkyl, R"' signifies hydrogen, hydroxy, lower alkyl or lower aminoalkanoyl, R5 signifies hydrogen, halogen, lower alkoxy or amino, R6 signifies lower alkyl, lower cycloalkyl, lower haloalkyl, phenyl or phenyl which is mono-, di- or trisubstituted by halogen, lower alkyl, hydroxy or lower alkoxy, R7 signifies hydrogen, lower alkyl or carboxy, R8 signifies hydrogen, hydroxy, lower alkoxy, amino, lower alkylamino or di-lower alkylamino and Y signifies an oxygen or sulphur atom, and pharmaceutically acceptable salts thereof. The products have an inhibitory action on the DNA-gyrase activity in bacteria. They can accordingly be used for the prevention or control of bacterial infections. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112574219-A |
| priorityDate | 1989-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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