http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2024306-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 |
| filingDate | 1990-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65c1ece603ba457781306424f2198b6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc49b628d4778141516c0d34b6610fb5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ee17e1e04e04d62709101c387c736f0 |
| publicationDate | 1991-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2024306-A1 |
| titleOfInvention | Cyclohexanol derivatives, production and use thereof |
| abstract | Abstract of the Disclosure The present invention relates to a compound of the formula: wherein A is halogen, N(O)mR1R2, N?R1R2R3?X?, S(O)nR1 or S?(O)mR1R2?X? where R1,R2 and R3 are each optionally substituted hydrocarbon or heterocyclic group, X? is a counter anion; m is an integer of 0 or 1; n is an integer of 0 to 2; R1 and R2 may form a nitrogen-containing or a sulfur-containing heterocyclic ring, which may further form a condensed ring, with the adjacent nitrogen atom or sulfur atom, and these nitrogen-containing or sulfur-containing heterocyclic rings may have substituents, B is O or NR4 where R4 is hydrogen or an optionally substituted lower alkyl or aryl group, D is 2-methyl-1-propenyl group or isobutyl group, and E is hydrogen, an optionally substituted hydrocarbon or an optionally substituted acyl group; provided that, when A is chlorine, E is an optionally substituted hydrocarbon or acyl excepting dinitrobenzoyl, a salt thereof, production and use thereof. The novel cyclohexanol derivatives of the present invention have angiogenesis inhibiting activity and anti-tumor activity, and they are used as anti-rheumatic agents, therapeutic agents of psoriasis, therapeutic agents of diabetic retinopathy and anti-tumor agents. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0797988-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2226085-A1 |
| priorityDate | 1989-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 460.