http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2023267-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8659631bf38b3a590c0d3edc265492c |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 |
filingDate | 1990-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb9ccb7a66f08581b172dd794a3bc81b |
publicationDate | 1991-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2023267-A1 |
titleOfInvention | Compounds |
abstract | B2818/Abs Abstract Novel Compounds A compound of formula (I) or a pharmaceutically acceptable salt thereof: (I) in which Z is a heterocyclic group in which Q represents a 3-membered divalent residue completing a 5-membered aromatic ring and comprises one or two heteroatoms selected from oxygen, nitrogen and sulphur, or three nitrogen atoms, any amino nitrogen being substituted by a C1-2 alkyl, cyclopropyl or propargyl group, and any ring carbon atom being optionally substituted by a group R1; or a group in which A1, A2 and A3 complete a 5-membered aromatic ring and Al is oxygen or sulphur, one of A2 and A3 is CR2 and the other is nitrogen or CR3, or A2 is oxygen B2818/Abs or sulphur, one of A1 and A3 is CR2 and the other is CR3; and R1, R2 and R3 are independently selected from hydrogen, halogen, CN, OR4, SR4, N(R4)2, NHCOR4, NHCOOCH3, NHCOOC2H5, NHOR4, NHNH2, NO2, COR4, COR5, cyclopropyl, C2-5 straight chain alkenyl, C2-5 straight chain alkynyl or C1-5 straight chain alkyl optionally terminally substituted with OR4, N(R4)2, SR4, CO2R4, CON(R4)2 or one, two or three halogen atoms, in which each R4 is independently hydrogen or C1-3 alkyl and R5 is OR4, NH2 or NHR4; or in which Z is a group -C(R7)-NR6 in which R6 is a group OR8, where R8 is C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, a group OCOR9 where R9 is hydrogen or R8, or a group NHR10 or NR11R12 where R10, R11 and R12 are independently C1-2 alkyl and R7 is hydrogen or C1-4 alkyl, subject to the proviso that when R6 is a group OCOR9 or NHR10, R7 is C1-4 alkyl. |
priorityDate | 1989-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 230.