| abstract |
The disclosure relates to cycloalkylene azoles of general Formula I (I), wherein is a carbocyclic or carbopolycyclic group optionally carrying at least one alkyl substituent, X is the grouping , an oxygen or sulfur atom, and Y and Z, independently of each other, are , or a nitrogen atom, as well as their pharmaceutically compatible addition salts with acids as well as processes for production thereof. The compounds possess strongly aromatase-inhibiting activity and are uitable for the preparation of medicinal agents. Methods for treating estrogen induced or stimulated tumors, male infertility, and impending cardiac infarction with these compounds are also provided as well as methods for inhbiiting female fertility. |