| abstract |
There are described compounds of the formula (see formula I) where n is 0 or 1; X is Q or NR2, R2 being hydrogen, loweralkyl or loweralkyl-carbonyl; Z is NO2 or NHR where R is hydrogen, loweralkyl, arylloweralkyl or loweralkylcarbonyl; and R1 is (see formula II, III, IV, V, VI, or VII) (see formula VIII, IX, X, XI, XII, or XIII) wherein R3 is hydrogen, loweralkyl or loweralkylcarbonyl; m is 1 or 2; each R4 is independently hydrogen or loweralkyl; and Y is hydrogen, halogen, loweralkyl, loweralkoxy or trifluoromethyl; which compounds are useful as topical antiinflammatory agents for the treatment of various dermatoses. |