http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2016829-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb8f3eba86915d967beefc175437273a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_058e0be30e00d53858c67167df60aed5 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 1990-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96273f133e844a6163570a48196adc17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50d661c0a2ebbeb86fe1e2f4c8c18f72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4c5aaad59982685acc4916ecce736ba |
| publicationDate | 1991-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2016829-A1 |
| titleOfInvention | 8,10-dideazatetrahydrofolic acid derivatives |
| abstract | ABSTRACT OF THE DISCLOSURE 8,10-Dideazatetrahydrofolic acid derivatives of the formula: where R1 and R2 are selected from hydrogen and alkyl having from one to about eight carbon atoms and the carboxylates and acid addition salts thereof, showing strong inhibition of L1210 murine leukemia cells in culture, modest inhibition of glycinamide ribotide transformylase and aminoimidazole carboxamide ribotide transferase, and insignificant inhibition of dihydrofolate reductase and thymidylate synthase enzymes. |
| priorityDate | 1988-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 595.