abstract |
ABSTRACT A thioformamide derivative of the formula I wherein:-R and R1 each independently represent an alkyl group; A represents either:-(1) a phenyl group which is optionally substituted; or (2) a heteroaromatic group (e.g. pyrid-3-yl, quinolin-3-yl); and Y represents:-an ethylene or methylene group or a direct bond. These compounds may be formulated as pharmaceutical preparations and have utility for the treatment of disorders associated with smooth muscle contraction. |