http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2013163-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39ae96c0ecc22ff90ff986371a3cea0f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-62 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 |
| filingDate | 1990-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23ccb00cf1cc0a36dc26af3af01f53b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3470a266638869f7af751e67d7d39b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2e336faa026fc3c9a2187567f1efc81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48079bc7bdd585adc6abe94600106a37 |
| publicationDate | 1990-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2013163-A1 |
| titleOfInvention | Benzopyran derivatives and processes for preparation thereof |
| abstract | ABSTRACT Benzopyran derivatives of the formula: wherein R1 and R2 are each lower alkyl, R3 is hydroxy or acyloxy and R4 is hydrogen, or R3 and R4 are linked together to from a bond, R5 is hydrogen or lower alkyl and R6 is hydrogen, lower alkyl or aryl, or R5 and R6 are linked together to form lower alkylene, R7 is cyano, acyl, halogen, nitro or lower alkyl, X is cyanoiminomethylene or sulfonyl, and Y is single bond, thio, imino which may have lower alkyl, provided that i) when R7 is cyano, X is cyanoiminomethylene and Y is thio or imino which may have lower alkyl, then R5 is hydrogen or lower alkyl and R6 is aryl; and ii) when R7 is cyano, R5 and R6 are linked together to form lower alkylene and X is sulfonyl, then Y is thio or imino which may have lower alkyl. These derivatives are useful as K+ channel activator, especially as vasodilating agent, for treating or preventing K+ channel mediated disease, for example vascular disorders such as hypertension, angina pectoris, cardiac insufficiency, peripheral and cerebral vascular diseases, atherosclerosis, arrhythmia, and the like in humans or animals. Processes for the preparation of these derivatives are also disclosed as well as pharmaceutical compositions containing these derivatives, methods of treatment using the derivatives and their uses as medicament, K+ channel activator and vasodilating agent. |
| priorityDate | 1989-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 184.