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filingDate 1990-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d674e42cfd4181d82479d3f38bb0d0f
publicationDate 1990-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2007337-A1
titleOfInvention Process for dissolving off an analyte from it's binding protein
abstract ABSTRACT The present invention provides a process for the dissolving off of an analyte bound to a binding protein by breakdown of the binding protein by a thiol cleaving SH groups in the alkaline range, wherein as SH group-cleaving thiol, there is used a 1,2-dithiolan-3-carboxylic acid of the general formula:- ( I ) in which n is a whole number of from 1 to 8. The present invention is also concerned with the use of this process for preparing samples for analytical or investigational processes for the determination of a liberated analyte and especially for immunoassays for vitamin B12.
priorityDate 1989-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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