| abstract |
1989-12-06, ATS/KGF 3343.010-DK Abstract Human insulin analogues having a positively charged amino acid residue, i.e. Lys or Arg, in position B28, i.e. in posi-tion 8 in the B-chain calculated from [GlyB20], and optional-ly being further modified in the C-terminal end of the B-chain from [PheB24] to the C-terminal amino acid residue and optionally A21 and/or B3 being different from Asn as well as insulin preparations containing the human insulin analogues are provided. |