| abstract |
ABSTRACT The absorption of antibiotics given through oral and rectal routes of administration is significantly enhanced by use of the antibiotic in conjunction with a two-component absorption enhancing system made up of an ether of a C6 to C18 alcohol and a polyoxyethylene glycol together with a second component selected from among polyoxyethylene glycol-C6 to C18 glyceride esters, C6 to C18 carboxylic acids or salts thereof, and esters of two or more C6 to C18 carboxylic acids, glycerol and a polyoxyethylene glycol. A carrier and adjuvants are usually included. These compositions can be administered in any convenient oral or rectal dosage form, including tablets, capsules, beadlets and suppositories. |