| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2105ff0016d39754931fadc3073de846 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-44 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57469
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-9453
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
1989-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e20d2c37a9a43939925932ebdd6ab0eb |
| publicationDate |
1990-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2000082-A1 |
| titleOfInvention |
Method for the detection of multiple drug resistant tumor cells and verapamil probes useful therein |
| abstract |
Abstract of the Disclosure A method for the detection of multiple drug resistant tumor cells is described which comprises the incubation of a sample of mammalian tumor cellular material with an effective binding amount of a labelled verapamil derivative to form an complex with any P-gp that is present, and then determining the amount of P-gp present by quantifying the amount of labelled verapamil derivative bound in the complex. Photoaffinity, radiolabelled and chemoaffinity derivatives of verapamil and the syntheses of such derivatives are described, as are a method of treatment for multiple drug resistant tumors and a diagnostic kit. |
| priorityDate |
1988-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |