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filingDate 1989-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2001-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91abc250009fca9dea52877a2b8f00e3
publicationDate 2001-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-1341328-C
titleOfInvention Sex-associated membrane proteins and methods for increasing the probability that offspring will be of a desired sex
abstract A method of sorting living cells based on DNA content. Mammalian sperm subpopulations enriched in X- or Y-sperm. X- and Y-enriched sperm-plasma-membrane vesicles. Substantially pure sex-associated membrane (SAM) proteins. Antibodies'binding to X-or Y-SAM proteins, essentially free of antibodies binding to Y- or X-SAM proteins respectively, or to the H-Y antigen. Semen samples enriched for X- or Y-sperm. Methods for increasing the probability that offspring will be male or female comprising the step of allowing a sperm from an enriched semen sample to fertilize an ovum. Methods for increasing the probability that offspring will be male or female comprising the step of immunizing a female with X- or Y-SAM proteins. Methods of decreasing fertility comprising the step of immunizing a female with both X- and Y-sperm. Methods of increas-ing the probability that mammalian offspring will carry a gene for a particular sex-chromosome linked trait.
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