| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-974
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-975
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-971 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1054 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-20 |
| filingDate |
1989-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c45e6f8bcb0d43f681e38eed937b229d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03ab7f39291ce80f1eb77610ca5c5d34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_448bfac1f15d211091b704299b05a87a |
| publicationDate |
2000-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-1340919-C |
| titleOfInvention |
Mouse monoclonal antibodies to hiv-1p24 and their use in diagnostic tests |
| abstract |
The present invention provides monoclonal antibodies demonstrating specific reactivity with HIV-I p24. One monoclonal antibody designated 31-42-19 recognizes an unique epitope on HIV-I p24 that is not immunogenic in humans. 31-42-19 also reacts with an antigenically cross reactive epitope on HIV-2 p24. Another monoclonal antibody designated 31-recognizes an epitope within a highly immunogenic region of HIV-I p24. The present invention also provides cell lines capable of producing these monoclonal antibodies. The invention also includes a highly sensitive enzyme immunoassay for the detection of HIV-I p24 in biological fluids, using a monoclonal antibody mixture. The present invention further provides methods for the use of these monoclonal antibodies for the detection of anti-HIV-I p24 antibodies and HIV-2 p24 antigen in biological samples. |
| priorityDate |
1988-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |