http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1340099-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca1d6d68b8b75bbd7786ae7cd89babc9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-163 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0087 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate | 1987-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1998-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf5aa2f41ab368d01d8ce7322a7d9d2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_256224c0fb2c55931986da80cdedb470 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a8cd036810318099721ef902bfc6664 |
| publicationDate | 1998-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1340099-C |
| titleOfInvention | Method for in vitro immunisation of lymphocytes for use in production ofhuman monoclonal antibodies and kit therefor |
| abstract | A method for the removal of, for in vitro immunisation, undesired cells from human lymphocyte containing cell populations is disclosed. For the method, use is made of lysosomotropic agents which are caused to act in vitro on human lymphocyte containing cell populations. Also disclosed is a method in the in vitro immunisation of lymphocytes for use in the production of human monoclonal antibodies. In this method, lysosomotropic agents are caused to act in vitro on human lymphocyte containing cell populations for removing cell populations having a negative effect on the in vitro immunisation, whereupon the lymphocytes are in vitro immunised antigen-specifically and immortalised. Finally, a kit for in vitro immunisation of lymphocytes for use in the production of human monoclonal antibodies is disclosed. The kit comprises as active constituents a container containing lymphokines and a container containing lysosomotropic agents. |
| priorityDate | 1986-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 119.