| abstract |
The invention is a chelate having a general formula wherein R1-4 is -CH2COOH; n is 1 to 5; X is a member selected from the group consisting of -N02, -NH2, -NCS, -NHCOCH2 - Z with Z being a member selected from the group consisting of Br and I; -COOH; and -OCH200CH; and M is a metal ion being a member selected from the group of elements consisting of Bi, Pb, Y, Cd, Hg, Al, Th, Sr, and Lanthanides. The invention can include a chelate wherein M is a copper ion and n is an integer from 2 to 5. The invention includes chelate conjugates of formula I and ligand conjugates of formula II: The invention also includes the use these compounds for treatment of cellular disorders and for diagnostic tests. |