| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D463-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D463-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D463-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate |
1989-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1996-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22626b1f28c9d29c5b4eb272bd862d7f |
| publicationDate |
1996-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-1338785-C |
| titleOfInvention |
Process for 1-carba(dethia)cephalosporins |
| abstract |
The invention provides a free radical process for preparing 1-carba(1-dethia)cephalosporin antibiotics with 2-substituted methylcephalosporin 1,1-dioxides wherein the substituent on the 2-methylene group is a free radical precursor group such as a phenyl or alkylseleno group. The latter dioxides are treated with a free radical initiator, e.g., a trialkyl-tin hydride or actinic radiation at 40°C to 150°C to provide the 1-carba-3-cephem and 1-carba-2-cephem products. The invention also provides free radical compounds formed as intermediates in the process. |
| priorityDate |
1988-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |