| abstract |
Novel O-alkylated oximes of the general formula I (I) wherein A is or wherein R1 and R2 are optionally substituted aromatic or heteroaromatic rings, R3 is hydrogen or lower alkyl, R4 is a nitrogen containing, substituted ring or an amino group carrying a substituted ring, and n and m indepen-dently are 0, 1 or 2, are potent inhibitors of GABA re-uptake from the synaptic cleft. |