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filingDate 1989-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1995-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ce72cbb51725c6b99cce3415afa8de3
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publicationDate 1995-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-1335654-C
titleOfInvention Monoclonal antibodies capable of recognizing gangliosides go__ and gt
abstract A monoclonal antibody specifically recognizes an epitope or an antigenic determinant represented by the following formula and specifically reacts therewith: The monoclonal antibody can be obtained by cultivating hybridoma cells which can be generated by a method comprising cell-fusing (A) B cells or lymphocytes obtained by immunizing an animal with a substance involving the epitope or the antigenic determinant represented by the foregoing formula and (B) myeloma cells. The monoclonal antibody shows high specificity to ganglioside GQ1b and ganglioside GT1a having a specific epitope and thus can detect the epitope in high sensitivity. Therefore, the antibody can be used for the elucidation of sugar chain's roles in cell functions and for studying the development of animals. Moreover, the monoclonal antibody would have various clinical applications.
priorityDate 1988-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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