| abstract |
Compounds of formula I in which: the R groups are independently hydrogen or lower alkyl, one of the R groups being attached to the thiochroman ring at the 6 or the 7 position; one of A and B is O or S and the other is -C(O)-,A being attached to the thiochroman ring at the 6 or 7-position, with one of the R groups being attached to the other of said 6 and 7 position; n is 0-5; and Z is H, an acid or acid derivative, an alcohol or alcohol derivative, acetal or acetal derivative or ketone or ketone derivative, or a pharmaceutically acceptable salt, have retinoid-like activity. |