| abstract |
A process for the preparation of a material for affinity chromatography is described, in which a sulfated poly-saccharide is bonded to a carrier material which has amino groups. For this purpose, a sulfated polysaccharide is treated with an oxidizing agent which oxidizes glycols to alde-hydes, with cleavage of the carbon chain, and this modi-fied sulfated polysaccharide is allowed to react with a carrier which has amino groups. It is possible using the described affinity material to adsorb proteins which bind to sulfated polysaccharides from solutions of these proteins and, where appropriate, then to desorb them, for example antithrombin III from blood plasma. |