| abstract |
ABSTRACT OF THE DISCLOSURE The present invention relates to novel compounds of the general formula (I) wherein R is a hydrogen atom or a trifluoromethyl, carboxy, C2-5-alkoxycarbonyl, cyano, benzoyl, sulfamoyl or C1-4 alkylsulfonyl group; R1 is a hydrogen atom or a linear or branched chain C1-4-alkyl, C1-4 alkylthio, C1-4 alkysulfonyl, benzylthio, benzyl-sulfonyl, phenyl, hydroxy or a mercapto group, and R2 is a hydrogen or chlorine atom, as well as their pharmaceutically acceptable salts. The compounds according to the invention possess diuretic and saluretic activity with an advantageous Na/k ratio. |