http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1332413-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1394e66eb648f9bf0a1f5507fe25b67b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 |
| filingDate | 1988-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1994-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4907ee2d1ad8c4e62562bf5c06805da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5990b610991065f11b863ccb0d009cbf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0404588a4461b8dbe7f1703f605c1f71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f6734cf3654edf29942415196fd9e52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9647a54a478af82ccf83f53adcfebece http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1807448d3b77c0465f58922cc93698f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d9c4567ff91597b77ee13ad25dcd7ba |
| publicationDate | 1994-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1332413-C |
| titleOfInvention | Camptothecin derivatives and process for preparing same |
| abstract | S P E C I F I C A T I O N Title: NEW CAMPTOTHECIN DERIVATIVES AND PROCESS FOR PREPARING SAME ABSTRACT OF THE DISCLOSURE New camptothecin derivatives, useful as antitumor agents or intermediates therefor, of the general formula (I) (I) wherein X is a lower alkyl group, and R is a hydrogen atom or the grouping -COY where Y is a linear or branched unsubstituted C1-C18alkyl group; a lower alkyl group substituted by a halogen atom or a lower alkylthio, amino, acylamino, hydroxyl, lower alkoxy, aryloxy or lower alkoxy-carbonyl group; a C3-C19 alkenyl, C3-C19 alkynyl or C3-C8 cycloalkyl group; a C3-C8 cycloalkyl group substituted by an acylamino-lower alkyl group; an N-acylpyrrolidyl group; a phenyl group; a phenyl group substituted by a halogen atom or a trifluoromethyl, nitro, amino, lower alkoxycarbonyl, lower alkyl, phenyl or lower alkoxy; a cinnamyl group; a benzyl group; a naphthyl group; a pyridyl group; a furyl group; or a thienyl group, as well as acid addition salts an? quaternary ammonium salts thereof, and a process for preparing the new camptothecin derivatives by subjecting 7-ethylcamptothecin to the treatment with an N-di-ethylenediamine followed by acylation. |
| priorityDate | 1987-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 157.