http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1331623-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-14 |
| filingDate | 1988-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1994-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_688620ee8621f288815a4cd22bc6cf30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c79e381ff4d64f98c0451eb4b220e1e5 |
| publicationDate | 1994-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1331623-C |
| titleOfInvention | Process for preparing 3-amino-1-benzylpyrrolidines |
| abstract | Process for preparing 3-amino-1-benzylpyrrolidines ABSTRACT OF THE DISCLOSURE A process for preparing a 3-amino-1-benzyl-pyrrolidino of the formula (I) in which R1 and R2 each independently is H or alkyl, and Ph is phenyl, comprising reacting a 1-benzyl-.DELTA.3-pyrroline-2,5-dione of the formula (II) in which R3 and R4 each independently is H or alkyl, with a nitrogen nucleophile of the formula R5NH2 (III) in which R5 is H, benzyl, naphthylmethyl or phenyl-CHR6, and R6 is C1-C6-alkyl or phenyl, to give an optionally substituted 3-amino-1-benzylpyrroli-dine 2,5-dione of the formula (IV) and, if R5 ? H, the protecting group R5 is subsequently cleaved off to give a 3-amino-1-benzylpyrrolidine-2,5-dione of the formula (IVa) and completely reducing the carbonyl groups to form the 3-amino-1-benzylpyrrolidine of the formula (I). |
| priorityDate | 1987-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 95.