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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-20
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J25-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-20
filingDate 1988-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1994-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dcbbd8c2a387700374fb204726c6e58
publicationDate 1994-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-1329212-C
titleOfInvention Process for the preparation of n-(2-chlorobenzyl)-2- (2-thienyl) ethylamine
abstract ABSTRACT This invention relates to a process for the preparation of N-(2-chlorobenzyl)-2-(2-thienyl)-ethylamine, a useful intermediate in the synthesis of ticlopidine which is a platelet aggregation inhibitor. According to the invention N-(2-chlorobenzyl)-2-(2-thienyl)-ethylamine is prepared by reaction of 2-thiophene acetonitrile with 2-chlorobenzylamine and hydrogen in the presence of a hydrogenation catalyst. This process is particularly advantageous since it ensures good yields while being unexpensive.
priorityDate 1987-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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