http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1327571-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 1988-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1994-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70889fe08a116119d370ef38a7485393 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0c1ca57329a962affc6f65da196876b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edb84c93bfa8529b9398ce07be63d84e |
| publicationDate | 1994-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1327571-C |
| titleOfInvention | Imidazodiazepine derivatives |
| abstract | Abstract The novel imidazodiazepine derivatives of the formula I wherein A together with the two carbon atoms denoted by .alpha. and .beta. signifies one of the groups and (a) (b) (c) R1 signifies one of the groups -CH=CH-R6 and -C?C-R6, (d) (e) R2 signifies hydrogen and R3 signifies lower alkyl or R2 and R3 together signify dimethylene or trimethylene, R4 and R5 each signify hydrogen, halogen. trifluoromethyl or lower alkyl and R6 signifies hydrogen, halogen, acyl or a saturated lower hydrocarbon group which is optionally mono- or di-substituted by hydroxy, lower alkoxy. (C3-C7)--cycloalkyl or oxo, whereby the compounds of formula I have the (S)- or (R,S)-configuration with reference to the carbon atom denoted by .gamma. when R2 and R3 together signify dimethylene or trimethylene and whereby the double bond present in group (d) has the E- and/or Z-configuration when R6 is different from hydrogen. possess valuable pharmacodynamic properties. They have as a common characteristic a pronounced affinity to the central benzodiazepine receptors and have either pro-nounced anxiolytic, anticonvulsant, muscle relaxant and sedative-hypnotic properties and/or they partially or completely selectively antagonize some or all activities which 1,4-benzodiazepines having tranquillizing activity or other substances display via the central benzodiazepine receptors. |
| priorityDate | 1987-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 209.